Lack of Sleep May Increase Chances of Death on Old Men

A new study conducted at the University of Minnesota revealed that disrupted rest and activity rhythms can be associated with the increased mortality rates among older men. Th study suggests that waking early, staying up late and severely disturbed sleep patterns on older men may have a detrimental impact on their health.

The experiment involved about 3,000 men older than 67 and they were tested for rest and activity biological rhythms using a device called an actigraph which they wore on heir wrists. This device tracked participants' movements, including the peak times of rest and activity, as well as the robustness of the activities for 24 hours a day for almost two years. Results showed that men who had peak activity times that were the earliest or latest, in comparison with the group average, had muhc greater risk of death.

Among the 3,000 participants, 180 died since the study begun.

"It's important to have a regular routine of waking and going to sleep," said Misti Paudel, M.P.H., principal investigator of the study and a member of the School of Public Health. "A good night sleep is important."

This is the first study to report strong associations between disturbed rest and activity rhythms and mortality rates in older men, who are still living in their homes (not institutionalized) - however, studies in cancer patients as well as institutionalized Alzheimer's patients have reported similar findings.

Lack of sleep can lead to a number of problems in older adults including depression, memory problems, and decreased attentiveness, and also can lead to serious health problems such as an increased risk of obesity, cardiovascular disease, and diabetes.

Another key study finding is that men with more robust rest/activity rhythms had much lower mortality rates. Having greater levels of activity during the day and/or lower levels of activity during the night (better sleep quality) are characteristics of robust rhythms.

Simple Exercise Can Cut Cancer Deaths in Men, Study Shows

A recent study published in the British Journal of Cancer revealed that men who exercise often are less likely to die from cancer than those who don't. The study found that men who walked or cycled for at least 30 minutes a day had a 34 per cent lower risk of dying from cancer than men who did less exercise or nothing at all.

The study involved a team of scientists from the Karolinska Institute in Sweden who monitored a number of 40,708 men aged between 45 and 79 years. During the seven years period of the study, 3,714 developed cancer and 1,153 died from the disease. The researchers suggest that half an hour of walking or cycling a day increased survival among these men by 33 per cent.

"These results clearly show for the first time, the effect that very simple and basic daily exercise such as walking or cycling has in reducing cancer death risk in middle-age and elderly men," one of the researchers, Professor Alicja said. "Additionally, this study threw up some really promising data on the role exercise can play in preventing cancer which we would like to explore further in future work."

They found that a more intensive program of walking and cycling for between an hour and an hour and a half a day, led to a l6 per cent lower incidence of cancer.

It's not entirely clear from this study what role exercise plays in preventing cancer in men, but it somehow proved that a healthy lifestyle can prevent up to half of all cancers - and regular exercise forms a key part of this. Cancer Research UK recommends maintaining a healthy body weight, eating sensibly and taking regular exercise as key to a healthy life - along with avoiding smoking.

Dehydrated Tomatoes May Prevent Prostate Cancer

Many studies and research have proven that tomatoes are actually good in preventing and fighting cancer. But another research suggests that the form or tomato product one eats could be the key to unlocking its prostate cancer-fighting potential. And it is dehydrated tomatoes.

According to the latest issue of the Cancer Research, a journal by the American Association for Cancer Research, the greatest protective effect of tomatoes from cancer, especially prostate cancer, comes from rehydrating tomato powder into tomato paste. This suggests that processing of edible plants through heating, grinding, mixing or drying dramatically increases their nutritional value.

The protective effect of tomato products against prostate cancer has been suggested in many studies, but researchers remain uncertain about the exact mechanisms. The study demonstrated that FruHis, an organic carbohydrate present in dehydrated tomato products, exerts a strong protective effect.

The research also evaluated the anti-cancer properties of FruHis and 14 other D-fructose amino acids and found that FruHis in a concentrated form protected against DNA damage known to lead to prostate cancer. When combined with lycopene, FruHis stopped cancerous cell growth more than 98 percent of the time.

Before this study, researchers attributed the protective effect of tomatoes to ascorbic acid, carotenoids, or phenolic compounds. FruHis may represent a novel type of potential dietary antioxidant. Experiments like these suggest that a combination of FruHis and lycopene should be investigated as a potential therapeutic anti-tumor agent, not just a prevention strategy.

The mission of the American Association for Cancer Research is to prevent and cure cancer. Founded in 1907, AACR is the world's oldest and largest professional organization dedicated to advancing cancer research.